Journal of Hainan Medical University
Meta‑analysis of the acupoint application therapy for stable chronic obstructive pulmonary disease
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Abstract:
Objective： To systematically evaluate the clinical efficacy and safety of acupoint application in the treatment of stable chronic obstructive pulmonary disease.Methods： A comprehensive search of various international and domestic databases was conducted， the search time is limited to recent ten years， collecting traditional Chinese medicine acupoint application in the treatment of chronic obstructive pulmonary disease in stable phase of randomized controlled trials.Literature screening， information extraction and literature quality evaluation were carried out independently by two researchers， and meta-analysis was carried out by Revman software.Results： A total of 42 RCTs with a total of 4 192 patients were included. The results of meta-analysis showed that， compared with the routine treatment of western medicine， the addition of acupoint application therapy can significantly increase the effective rate［RR=1.23，95%CI（1.19，1.27），P<0.000 01］ and FEV1/FVC［MD=4.46，95%CI（3.17，5.76），P<0.000 01］，and significantly improved BODE index［MD=-0.63，95%CI（-0.87，-0.40），P<0.000 01］，SGRQ score［MD=-6.77，95%CI（-9.81，-3.72），P<0.000 01］，CAT score［MD=-3.33，95%CI（-3.87，-2.79），P<0.000 01］ and TCM syndrome integral［MD=-3.51，95%CI（-3.96，-3.06），P<0.000 01］.The differences is statistically significant and the safety is good.Conclusion： On the basis of routine treatment of COPD western medicine， acupoint application therapy can significantly improve the clinical symptoms of patients with less adverse reactions. However， due to the limitations of the research， high‑quality research is still needed to provide further evidence.
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Project Supported:
Traditional Chinese Medicine Research Project of Hubei Provincial Administration of Traditional Chinese Medicine from 2023 to 2024 (ZY2023F138), and the Construction Project of the "National Famous Traditional Chinese Medicine Inheritance Studio" of the National Administration of Traditional Chinese Medicine [Guozhong Pharmaceutical Renjiao Fa (2022)No. 5]
Clc Number:
R246.1
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